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January 1, 2004EP Europace18 citations

Prognostic significance of right ventricular extrasystoles

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BZB. ZweytickPPP. Pignoni-MoryGZG. Zweytick

Key Result

Patients with right ventricular extrasystoles had a good prognosis, with no sustained ventricular tachycardia, syncope, or sudden death occurring over a mean follow-up of 7.2 years.

Study Design

Type

Cohort (n=56)

Structured PICO

What is the long-term prognosis of patients with right ventricular extrasystoles without structural heart disease?

P
Population
56 consecutive patients with right ventricular extrasystoles, free of structural cardiovascular or lung diseases, followed for a mean of 7.2 years.
O
Outcome
Prognosis in terms of morbidity and mortality (sustained ventricular tachycardia, syncope, or sudden death)hard clinical

Patients with right ventricular extrasystoles without structural heart disease have a benign long-term prognosis, regardless of the presence of echomorphologic right ventricular abnormalities.

Main Result

Absolute Event Rate: 21.9% vs 33.3%

Abstract

UNLABELLED: Extrasystoles (RVES) from the right ventricular outflow tract (RVOT) are a common arrhythmia in routine ECGs. METHODS: In this prospective study 56 consecutive patients with RVES (22 males, 34 females) were examined for morphological and/or functional right ventricular (RV) abnormalities by 12-lead, Holter, exercise ECGs, transthoracic echocardiography and signal averaging. The follow-up time was 3.1-15.8 years (arithmetic mean +/- SD = 7.2 +/- 1.6 years; median, 6.9 years). Patients with hyperthyroidism, structural cardiovascular and/or lung diseases were excluded. RESULTS: A total of 57.1% of the patients with RVES presented with echomorphologic abnormalities of the right ventricle (RV). In 26.8% the echomorphologic right ventricular abnormalities progressed in 33.3% of patients with normal RVs at baseline (group I) and in 21.9% of those with abnormal RVs at baseline (group II). No significant differences were found between the 2 patient groups in terms of age at onset, family history, ECG changes, late potentials and malignant right ventricular outflow tract arrhythmias on 24-h and exercise ECGs. While females predominated in group I, males were numerous in group II (p = 0.006). Sustained ventricular tachycardia, syncope or sudden death were absent throughout the follow-up. CONCLUSION: Patients with RVES carry a good prognosis in terms of morbidity and mortality no matter whether echomorphologic abnormalities are present or not.

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Cite This Study

Zweytick et al. (2004) conducted a cohort in Right ventricular extrasystoles (RVES) (n=56). Echomorphologic abnormalities of the right ventricle at baseline vs. Normal right ventricle at baseline was evaluated on Progression of echomorphologic right ventricular abnormalities. Patients with right ventricular extrasystoles had a good prognosis, with no sustained ventricular tachycardia, syncope, or sudden death occurring over a mean follow-up of 7.2 years.

synapsesocial.com/papers/6a1f39fbc333d7dc9c232e81https://doi.org/10.1016/j.eupc.2003.11.010
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