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June 3, 2026PNAS Nexus0 citationsOpen Access

Physics informed differentiable solvers for learning parametric solution manifolds in heterogeneous physical systems

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MPMilad PanahiGPGiovanni PortaMRMònica Riva

Key Points

  • This research aims to quantify parametric uncertainty in partial differential equations related to heterogeneous physical systems.
  • Reformulated a Physics-Informed Neural Network (PINN) as a differentiable solver.
  • Using a single training run to circumvent re-training for new parameter instances.
  • Integrated a differentiable decoder within the physics-informed loss function for on-the-fly reconstruction.
  • Accurate, mass-conserving flow solutions were achieved.
  • Supported efficient uncertainty quantification.
  • Provided a general methodology for modeling heterogeneous systems using physics constraints.

Abstract

Abstract Quantifying parametric uncertainty in partial differential equations (PDEs) is a central challenge to our ability to model the behavior of heterogeneous systems. This challenge is relevant to a variety of fundamental and application-oriented implications where system properties exhibit significant (and often uncertain) spatial heterogeneity. We address this by reformulating a Physics-Informed Neural Network (PINN) as a differentiable solver that learns the continuous solution manifold for steady-state Darcy flow. Our framework requires only a single training run, circumventing the need for costly re-training for each new parameter instance. The approach is demonstrated through two representations of spatially heterogeneous hydraulic conductivity fields: a direct analytical form and a novel data-driven formulation resting on an autoencoder to create a low-dimensional latent encoding. A key innovation is the integration of the differentiable decoder into the physics-informed loss function, enabling on-the-fly reconstruction of complex conductivity fields. The approach yields accurate, mass-conserving flow solutions and supports efficient uncertainty quantification, providing a general methodology for physics-constrained data-driven modeling of heterogeneous systems.

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Cite This Study

Panahi et al. (2026) studied this question.

synapsesocial.com/papers/6a1fc42cdee9eb8c0dce5c29https://doi.org/10.1093/pnasnexus/pgag195
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