This research aims to explore urotensin II's dual roles in chronic kidney disease, providing insights from clinical and mechanistic perspectives.
Clinical evaluations of urotensin II levels in chronic kidney disease patients.
Mechanistic analyses to assess urotensin II's effects on renal function and pathology.
Identified varying impacts of urotensin II on kidney function depending on the disease stage.
Demonstrated urotensin II's potential as both a protective and harmful factor in kidney health.
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Wang et al. (2026) studied this question. Urotensin II demonstrates conflicting clinical and mechanistic roles in the pathogenesis and progression of chronic kidney disease.