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June 3, 2026Disease Models & Mechanisms0 citationsOpen Access

First person – Amy Bongetti

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Key Points

  • The aim is to understand skeletal muscle dysfunction and recovery in critically ill conditions using refined animal models.
  • Interviews with first authors of published research papers in Disease Models & Mechanisms.
  • Focus on evaluating muscle dysfunction in a zymosan model of critical illness using mice.
  • Discovering mechanisms underlying muscle dysfunction in critical illness.
  • Identifying pathways that may inform therapeutic strategies for muscle wasting.

Abstract

First Person is a series of interviews with the first authors of a selection of papers published in Disease Models & Mechanisms, helping researchers promote themselves alongside their papers. Amy Bongetti is first author on ‘ Evaluating skeletal muscle dysfunction and recovery in a zymosan model of critical illness in mice’, published in DMM. Amy is an associate research fellow in the lab of Professor Gordon Lynch at The University of Melbourne, Victoria, Australia, investigating skeletal muscle wasting and weakness in critically ill patients, particularly in the refinement of animal models to improve mechanistic understanding of this condition and the translation of therapeutics from bench to bedside.

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Cite This Study

A 2026 study studied this question.

synapsesocial.com/papers/6a1fc56bdee9eb8c0dce6e5dhttps://doi.org/10.1242/dmm.053009
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