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June 3, 2026Eskisehir Medical Journal Eskisehir City Hospital0 citationsOpen Access

Comparative Analysis of Scoring Systems for Predicting Rehospitalisation, Mortality and Adverse Outcomes in the Intensive Cardiovascular Care Unit

AAArzu Neslihan AkgünSHSenem HasırcıEKEmir Karaçağlar

Key Result

The SAPS II, MPM II, and SOFA scoring systems significantly predicted mortality in intensive cardiovascular care unit patients, with SAPS II demonstrating the highest predictive accuracy (AUC 0.78, p=0.000).

Key Points

  • This study aims to compare four scoring systems for their effectiveness in predicting mortality, rehospitalisation, and adverse outcomes in ICCU patients.
  • Included 139 patients admitted to the ICCU from January 2020 to January 2022.
  • Used APACHE II, SAPS II, MPM II, and SOFA scoring systems, calculated from the first 24 hours after admission.
  • Retrospective analysis performed to assess correlation with outcomes such as mortality and rehospitalisation.
  • Mortality rate in the ICCU was 16.5%.
  • MPM II, SAPS II, and SOFA scores were significantly associated with mortality, while APACHE II was not.
  • MPM II and APACHE II scores were significant predictors of rehospitalisation, but no significant association with MACE was found.

Study Design

Type

Observational (n=139)

Multicenter

No

Structured PICO

Do APACHE II, SAPS II, MPM II, and SOFA scores predict mortality, rehospitalisation, MACE, and length of stay in patients admitted to the intensive cardiovascular care unit?

P
Population
139 adult patients (mean age 74 years, 51.8% female) admitted to the intensive cardiovascular care unit, evaluated retrospectively to compare the predictive value of four clinical scoring systems.
E
Exposure
Retrospective calculation of APACHE II, SAPS II, MPM II, and SOFA scores using data from the first 24 hours after ICCU admission.
O
Outcome
Mortality, rehospitalisation, major adverse cardiovascular events (MACE), and length of stay (LOS).hard clinical

The MPM II score demonstrates utility in predicting both mortality and rehospitalisation for patients admitted to the intensive cardiovascular care unit.

Main Result

Effect estimate: AUC 0.78 for SAPS II

p-value: p=0.000

Limitations

  • Small sample size may have limited the ability to detect significant relationships for MACE
  • Retrospective study design
  • Longer follow-up is needed to better understand associations
  • small sample size
  • heterogeneity of patient conditions

Abstract

Introduction: The intensive cardiovascular care unit (ICCU) specializes in treating cardiovascular disease patients, often those with comorbidities. Our study conducted a comparative analysis of four scoring systems — APACHE II, SAPS II, MPM II, and SOFA— to evaluate their effectiveness in predicting mortality, rehospitalisation, major adverse cardiovascular events (MACE), and length of stay (LOS) in patients admitted to the ICCU. Methods: We included 139 patients admitted between January 2020 and January 2022 to the ICCU. The prognostic scales used were the APACHE II, SAPS II, MPM II, and SOFA, which were retrospectively calculated using data from the first 24 hours after ICCU admission. Results: The most common diagnosis for admission to the ICCU was decompensated heart failure. The mortality rate was 16.5%. The MPM II, SAPS II, and SOFA scores were significantly associated with mortality. The APACHE II score did not significantly correlate with mortality, possibly due to the heterogeneity of patient conditions. The APACHE II and MPM II scores were significant predictors of rehospitalisation, with no significant associations found for the SOFA and SAPS II scores. All four scoring systems were significantly associated with tells, indicating that higher scores predict longer stays in the ICCU. No significant association was found between the scores and MACE, possibly due to the study's small sample size. Conclusion: This study is the first to evaluate these scores for ICCU patients and to explore outcomes such as rehospitalisation, MACE, and LOS. This highlights the potential of the MPM II score for predicting both mortality and rehospitalisation, suggesting that these scoring systems could improve clinical practice.

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Cite This Study

Akgün et al. (2026) conducted an observational in Cardiovascular disease requiring intensive care (n=139). APACHE II, SAPS II, MPM II, and SOFA scoring systems was evaluated on Mortality prediction (AUC 0.78 for SAPS II, p=0.000). The SAPS II, MPM II, and SOFA scoring systems significantly predicted mortality in intensive cardiovascular care unit patients, with SAPS II demonstrating the highest predictive accuracy (AUC 0.78, p=0.000).

synapsesocial.com/papers/6a1fc5d7dee9eb8c0dce744bhttps://doi.org/10.48176/esmj.2026.254
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