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June 30, 2022Biomedical & Pharmacology Journal2 citationsOpen Access

Evaluation of changes in Blood Pressure (BP) and Heart Rate (HR) among controlled Hypertensive and Normotensive Patients before and after receiving Dental Local Anesthesia (DLA) with Adrenaline: A Prospective Study

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FAFareedi Mukram AliGIGhassan M IryaniMBMohammed Mousa H. Bakri

Key Result

Dental local anesthesia with epinephrine was preceded by significant alterations in systolic blood pressure in all patients and heart rate in hypertensive patients.

Study Design

Type

Observational (n=40)

Multicenter

No

Structured PICO

Does dental local anesthesia with epinephrine cause significant changes in blood pressure and heart rate in controlled hypertensive and normotensive patients?

P
Population
40 adult patients, comprising 20 normotensive and 20 controlled hypertensive individuals, evaluated during dental local anesthesia.
E
Exposure
Dental local anesthesia using 2% lidocaine with epinephrine
C
Comparator
Normotensive patients (Group A) vs controlled hypertensive patients (Group B)
O
Outcome
Changes in blood pressure (BP) and heart rate (HR) measured at three temporal locations: waiting room, in clinic before, and after administration of local anesthesiasurrogate

Endogenous catecholamines related to dental anxiety appear to cause more significant hemodynamic disturbances than the epinephrine in local anesthesia, particularly in hypertensive patients.

Abstract

To evaluate the alterations in blood pressure (BP) and heart rate (HR) among hypertensive and normotensive patients receiving dental local anesthesia using 2% lidocaine with epinephrine. This prospective observational study was carried out at the College of Dentistry, Jazan, KSA. A total of 40 adult patients were included in the study. They were divided into two groups (n=20). Group “A” included normotensive patients and group “B” included controlled hypertensive patients. The BP and HR were measured by a sphygmomanometer and pulse oximeter in three different temporal locations: on arrival to the waiting room, and in clinic before and after administration of local anesthesia. The mean values of the measurements in the three locations; the waiting area, clinic before and after the administration of DLA, were noted. The only significant alterations were found in the Systolic Blood Pressure (SBP) of both hypertensive and normotensive patients before the administration of DLA and in the HR of hypertensive patients again only before the administration of DLA. Endogenous catecholamines are more significant in causing hemodynamic disturbances in dental patients. Hypertensive patients seem to be more vulnerable to these disturbances.

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Cite This Study

Ali et al. (2022) conducted an observational in Hypertension (n=40). Dental local anesthesia using 2% lidocaine with epinephrine vs. Normotensive patients was evaluated on Alterations in blood pressure (BP) and heart rate (HR). Dental local anesthesia with epinephrine was preceded by significant alterations in systolic blood pressure in all patients and heart rate in hypertensive patients.

synapsesocial.com/papers/6a1ff4643224f8dacd0dad4bhttps://doi.org/10.13005/bpj/2413
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