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February 1, 1982Circulation306 citations

Evaluation of a QRS scoring system for estimating myocardial infarct size. I. Specificity and observer agreement.

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GWGalen S. WagnerCFChristopher J. FreyeSPSebastian T. Palmeri

Key Result

A 29-point QRS scoring system achieved 98% specificity for identifying myocardial infarction when a score >2 was required, with at least 91% intra- and interobserver agreement.

Key Points

  • The study aims to evaluate a QRS scoring system for its ability to estimate myocardial infarct size and assess specificity and observer agreement.
  • Evaluated a simplified QRS scoring system using 12-lead ECG measurements in 50 subjects.
  • Established specificity of each of the 37 criteria for the scoring system.
  • Measured intra- and interobserver agreement for the scoring criteria.
  • Achieved 98% specificity when requiring a score of more than 2 points to identify myocardial infarcts.
  • Each scoring criterion demonstrated at least 91% intra- and interobserver agreement.
  • Evaluated sensitivity correlating point score with infarct size in subsequent studies.

Study Design

Type

Observational (n=50)

Structured PICO

Does a 29-point QRS scoring system demonstrate high specificity and observer agreement for identifying myocardial infarction?

P
Population
Subjects with minimal likelihood of myocardial infarction to establish specificity, and 50 patients evaluated for intra- and interobserver agreement of a QRS scoring system.
E
Exposure
29-point QRS scoring system based on 37 criteria from standard 12-lead ECG
O
Outcome
Specificity of the QRS scoring system and intra- and interobserver agreementsurrogate

A simplified 29-point QRS scoring system from standard 12-lead ECGs demonstrates high specificity and excellent observer agreement for identifying myocardial infarction.

Limitations

  • Sensitivity and correlation between point score and infarct size in patients with proven infarcts were not evaluated in this study.
  • Sensitivity and correlation with infarct size not evaluated in this study

Abstract

We evaluated a simplified version of a previously developed QRS scoring system for estimating infarct size using observations of Q- and R-wave durations and R/Q and R/S amplitude ratios in the standard 12-lead ECG. Groups of subjects with a minimal likelihood of having myocardial infarcts and minimal likelihood of having common noninfarction sources of QRS modification were studied to establish the specificity of each of the 37 criteria. Only two criteria required modification to achieve 95% specificity. These 37 criteria form the basis of a 29-point QRS scoring system. A 98% specificity was achieved when a score of more than 2 points was required to identify a myocardial infarct. Fifty patients were studied to determine the intra- and interobserver agreement with this scoring system. Each criterion achieved at least 91% intra- and interobserver agreement. These impressive levels of specificity and observer agreement must be matched by high sensitivity of the scoring system and a good correlation between the point score and infarct size in patients with proven infarcts if the point score is to be useful for detecting and sizing infarcts. Sensitivity and correlation between point score and infarct size are evaluated in later studies in this series. The standard ECG is inexpensive and can be obtained repetitively and noninvasively; its QRS complex may be an important means of estimating the size, presence and location of myocardial infarcts.

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Cite This Study

Wagner et al. (1982) conducted an observational in Myocardial infarction (n=50). QRS scoring system was evaluated on Specificity and intra- and interobserver agreement. A 29-point QRS scoring system achieved 98% specificity for identifying myocardial infarction when a score >2 was required, with at least 91% intra- and interobserver agreement.

synapsesocial.com/papers/6a1ff9a82065d284090dbbf5https://doi.org/10.1161/01.cir.65.2.342
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