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November 1, 1976Archives of Disease in Childhood320 citationsOpen Access

Estimation of glomerular filtration rate from plasma creatinine concentration in children.

RCR CounahanCCC ChantlerSGSazlina Shariff Ghazali

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Abstract

The relation between the true plasma creatinine concentration (Pc) and the glomerular filtration rate corrected for body surface area (GFR/SA) was investigated in 108 individuals, and the following formula was derived: GFR/SA (ml/min per 1-73m2SA) = 0-43 Ht (cm)/Pc (mg/100 ml). This formula was tested in a second group of 83 children, and its accuracy and precision was compared to the 24-hour creatinine clearance. It was found to be superior to the creatinine clearance overall, and was as good, even if all results involving suspect 24-hour-urine collections were eliminated from analysis. The formula in SI usage is: GFR/SA (ml/min per 1-73 m2SA) = 38 Ht (cm)1Pc (mumol/l).

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Cite This Study

Counahan et al. (1976) studied this question.

synapsesocial.com/papers/6a2008ead40b4a263065b844https://doi.org/10.1136/adc.51.11.875
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