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December 1, 2003Applied and Environmental Microbiology323 citationsOpen Access

Antifungal 3-Hydroxy Fatty Acids from Lactobacillus plantarum MiLAB14

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JSJörgen SjögrenJMJesper MagnussonABAnders Broberg

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Abstract

We report the identification and chemical characterization of four antifungal substances, 3-(R)-hydroxydecanoic acid, 3-hydroxy-5-cis-dodecenoic acid, 3-(R)-hydroxydodecanoic acid and 3-(R)-hydroxytetradecanoic acid, from Lactobacillus plantarum MiLAB 14. The concentrations of the 3-hydroxy fatty acids in the supernatant followed the bacterial growth. Racemic mixtures of the saturated 3-hydroxy fatty acids showed antifungal activity against different molds and yeasts with MICs between 10 and 100 micrograms ml-1.

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Sjögren et al. (2003) studied this question.

synapsesocial.com/papers/6a200ac49d62e9997c04ba94https://doi.org/10.1128/aem.69.12.7554-7557.2003
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