PulseExploreJournal ClubDebatesTrendingResearchersJournals
Instagram
HomeExploreJournal ClubTrending
Synapse
⌘+K
Synapse
October 15, 1996Proceedings of the National Academy of Sciences234 citationsOpen Access

Paternal and maternal DNA lineages reveal a bottleneck in the founding of the Finnish population.

View Full Paper
ASAntti SajantilaASAbdel Halim SalemPSPeter Savolainen

Key Points

Key points are not available for this paper at this time.

Abstract

An analysis of Y-chromosomal haplotypes in several European populations reveals an almost monomorphic pattern in the Finns, whereas Y-chromosomal diversity is significantly higher in other populations. Furthermore, analyses of nucleotide positions in the mitochondrial control region that evolve slowly show a decrease in genetic diversity in Finns. Thus, relatively few men and women have contributed the genetic lineages that today survive in the Finnish population. This is likely to have caused the so-called "Finnish disease heritage"-i.e., the occurrence of several genetic diseases in the Finnish population that are rare elsewhere. A preliminary analysis of the mitochondrial mutations that have accumulated subsequent to the bottleneck suggests that it occurred about 4000 years ago, presumably when populations using agriculture and animal husbandry arrived in Finland.

Ask AI
Helpful
Bookmark
Share
View Full Paper

Cite This Study

Sajantila et al. (1996) studied this question.

synapsesocial.com/papers/6a2020b37a14b33c8ba1b0f3https://doi.org/10.1073/pnas.93.21.12035
Ask AI
Helpful
Bookmark
Share
View Full Paper