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February 1, 1975British Journal of Clinical Pharmacology74 citationsOpen Access

Changes in drug metabolism with increasing age: 1. warfarin binding and plasma proteins.

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MHM J HayesMLM J LangmanASA. H. Short

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Abstract

1 A decrease was found in the binding capacity of elderly people for warfarin. 2 The decrease in binding correlated with a fall in plasma albumin concentrations. 3 No changes in the association constant were observed.

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Hayes et al. (1975) studied this question.

synapsesocial.com/papers/6a203eac5384fe21d78fd8dbhttps://doi.org/10.1111/j.1365-2125.1975.tb00474.x
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