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February 8, 2016European Journal of Preventive Cardiology80 citations

The long-term effects of a randomized trial comparing aerobic interval versus continuous training in coronary artery disease patients: 1-year data from the SAINTEX-CAD study

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NPNele PattynLVLuc VanheesVCVéronique Cornelissen

Key Result

Aerobic interval training and aerobic continuous training similarly preserved physical fitness and physical activity levels at 1-year follow-up (p-interaction > 0.05).

Study Design

Type

RCT (n=200)

Multicenter

Yes

Structured PICO

Does aerobic interval training compared to aerobic continuous training improve long-term physical fitness and physical activity in patients with coronary artery disease?

P
Population
200 patients with coronary artery disease randomized to 12 weeks of aerobic interval or continuous training and followed for 1 year.
I
Intervention
Aerobic interval training (AIT) for 12 weeks
C
Comparator
Aerobic continuous training (ACT) for 12 weeks
O
Outcome
Physical fitness (VO2, heart rate and workload at peak and at thresholds) and physical activity (steps, active energy expenditure, physical activity duration) at 12 monthssurrogate

Short-term center-based aerobic interval training and continuous training yield comparable and sustained 1-year improvements in physical fitness and activity in patients with coronary artery disease.

Main Result

p-value: p=>0.05

Abstract

BACKGROUND: Aerobic interval training (AIT) and aerobic continuous training (ACT) both improve physical fitness (peak VO2) in coronary artery disease patients. However, little is known about the long-term effects of AIT and ACT on peak VO2 and exercise adherence. DESIGN: This study is a randomized clinical multicenter trial. METHODS: In total, 163 patients were assessed after 12 weeks of AIT or ACT and 12 months after their enrollment. Physical fitness and physical activity measures served as the primary outcomes, and peripheral endothelial function, cardiovascular risk factors and quality of life (QoL) served as the secondary outcomes. RESULTS: Twenty-six patients dropped out during the intervention; 11 were lost during the follow-up period. Dropouts (n = 37) consisted of more women (p = 0.001) compared to completers (n = 163). Physical fitness (VO2, heart rate and workload at peak and at thresholds) and physical activity (steps, active energy expenditure kcal, physical activity duration minutes) were preserved at the 1-year follow-up (p-time > 0.05) after both AIT and ACT (p-interaction > 0.05). Forty percent of patients showed increased peak VO2, 52% showed increased active energy expenditure and 91.2% met the recommended levels of 150 minutes/week of moderate physical activity (p-group > 0.05). Further, peripheral endothelial function, QoL and cardiovascular risk factors, except systolic blood pressure (p-time 0.05) after both AIT and ACT (p-interaction > 0.05). CONCLUSION: The short-term improvements of center-based AIT and ACT on physical fitness, physical activity, peripheral endothelial function, cardiovascular risk factors and QoL are sustained after a 1-year follow-up period. The majority of patients (>90%) met the recommended physical activity levels of 150 minutes/week.

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Cite This Study

Pattyn et al. (2016) conducted an RCT in Coronary artery disease (n=200). Aerobic interval training (AIT) vs. Aerobic continuous training (ACT) was evaluated on Physical fitness and physical activity measures (p=>0.05). Aerobic interval training and aerobic continuous training similarly preserved physical fitness and physical activity levels at 1-year follow-up (p-interaction > 0.05).

synapsesocial.com/papers/6a207f78ca5c5b2ddfa5e323https://doi.org/10.1177/2047487316631200
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