Time-resolved three-dimensional relative pressure fields within the human heart can be noninvasively assessed by combining phase-contrast MRI velocity measurements with the pressure Poisson equation.
Noninvasive simultaneous assessment of cardiac pressure and flow phenomena using 3D phase-contrast MRI and computational fluid mechanics provides a new tool for studying cardiac fluid dynamics.
Understanding cardiac blood flow patterns is important in the assessment of cardiovascular function. Three-dimensional flow and relative pressure fields within the human left ventricle are demonstrated by combining velocity measurements with computational fluid mechanics methods. The velocity field throughout the left atrium and ventricle of a normal human heart is measured using time-resolved three-dimensional phase-contrast MRI. Subsequently, the time-resolved three-dimensional relative pressure is calculated from this velocity field using the pressure Poisson equation. Noninvasive simultaneous assessment of cardiac pressure and flow phenomena is an important new tool for studying cardiac fluid dynamics.
Ebbers et al. (2002) studied Normal cardiac function (n=1). Time-resolved three-dimensional phase-contrast MRI and pressure Poisson equation was evaluated on Calculation of time-resolved three-dimensional relative pressure. Time-resolved three-dimensional relative pressure fields within the human heart can be noninvasively assessed by combining phase-contrast MRI velocity measurements with the pressure Poisson equation.