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October 6, 1978Science140 citations

Manufactured Hexaparental Mice Show That Adults Are Derived from Three Embryonic Cells

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CMClement L. MarkertRPRobert M. Petters

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Abstract

Two female chimeric mice have been produced by aggregates of three genetically marked eight-cell embryos. All three embryonic genotypes are clearly expressed in the pigment pattern of the adults. These hexaparental mice together with their littermates demonstrate that, in the 64-celled blastocyst, at least three cells, and probably only three, are the source of all adult tissues.

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Cite This Study

Markert et al. (1978) studied this question.

synapsesocial.com/papers/6a208d6eb15f64b498301e45https://doi.org/10.1126/science.694518
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