A weight-loss diet alone or combined with resistance training shifted the association between abdominal fat depots and glucose metabolism from the L4-L5 region to the L2-L3 region.
RCT (n=34)
randomized
Does a weight-loss diet alone or combined with progressive resistance training alter the association between abdominal fat depots and cardiometabolic risk in obese women?
Weight loss alone or with resistance training shifts the association between abdominal fat depots and glucose metabolism to the L2-L3 region, highlighting its importance for predicting insulin resistance.
BACKGROUND/AIMS: A weight-loss diet alone or combined with a progressive resistance training program induced different adaptations on cardiometabolic risk, i.e. regional changes in visceral adipose tissue (VAT) and subcutaneous adipose tissue (SAT) volume distribution patterns. We hypothesized that a heterogeneous adipose tissue metabolism may exist between visceral fat at different discal levels. METHODS: Thirty-four obese women, aged 40-60 years, were randomized to three groups: a control group (n = 9), a diet group (WL; n = 12) with a caloric restriction of 500 kcal/day during 16 weeks, or a diet-plus-resistance-training group (WL+RT; n = 13) with the same caloric restriction and a 16-week resistance training of 2 sessions per week. RESULTS: The association pattern between abdominal fat depots and glucose metabolism variables showed a change from the L4-L5 region (preintervention) to VAT L2-L3 and SAT L2-L3 in the WL and WL+RT groups, respectively. It is noteworthy that accumulation of fat in the midthigh was not characterized by a more favorable lipid profile or glucose metabolism. CONCLUSION: Our results reinforce the importance of considering L2-L3 images to predict insulin resistance after a weight-loss diet, alone or combined with resistance training.
García‐Unciti et al. (2012) conducted an RCT in obesity (n=34). Weight-loss diet alone or combined with progressive resistance training vs. control group was evaluated on Association pattern between abdominal fat depots and glucose metabolism variables. A weight-loss diet alone or combined with resistance training shifted the association between abdominal fat depots and glucose metabolism from the L4-L5 region to the L2-L3 region.
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