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November 1, 1948The Journal of Experimental Medicine299 citationsOpen Access

Specific Serum Agglutination of Erythrocytes Sensitized With Extracts of Tubercle Bacilli

GMGardner MiddlebrookRDRené Dubos

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Abstract

A hemagglutination reaction has been described between sheep erythrocytes treated with a component of a polysaccharide fraction of mammalian tubercle bacilli and the sera of experimental animals or of tuberculous patients. Evidence has been presented for the specificity of this reaction. A modification of the test, involving an inhibition reaction, has been developed for the detection and quantitation of minute amounts of the material responsible for the hemagglutination reaction.

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Cite This Study

Middlebrook et al. (1948) studied this question.

synapsesocial.com/papers/6a20aad06fd408b32f72e0c2https://doi.org/10.1084/jem.88.5.521
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