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October 1, 1969Journal of Virology109 citationsOpen Access

Molecular Weight of Poliovirus Ribonucleic Acid

NGNicole GranboulanMGMarc Girard

Structured PICO

P
Population
Purified poliovirus single- and double-stranded ribonucleic acids (RNA)
I
Intervention
Electron microscopy and sedimentation coefficient analysis
C
Comparator
Tobacco mosaic virus RNA (for sedimentation coefficient comparison)
O
Outcome
Molecular weight and length of poliovirus RNAsurrogate

This basic science study determined the molecular weight of poliovirus RNA to be 2.6 x 10(6) daltons.

Abstract

Purified poliovirus single- and double-stranded ribonucleic acids (RNA) were examined by electron microscopy. The length of both molecules was found to be 2.37 mum. The uncorrected sedimentation coefficient for single-stranded RNA is 33S, as compared to 27S for the RNA of tobacco mosaic virus. It is calculated from these results that the molecular weight of the sodium form of poliovirus is 2.6 x 10(6) daltons.

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Cite This Study

Granboulan et al. (1969) studied this question.

synapsesocial.com/papers/6a20d61134bef10fdaeb0bfehttps://doi.org/10.1128/jvi.4.4.475-479.1969
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