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March 1, 2003Annual Review of Neuroscience333 citations

Cellbiology of Thepresynapticterminal

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VMVenkatesh N. MurthyHarvard University
Pietro De Camilli
Pietro De CamilliSociety for Neuroscience

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Abstract

The chemical synapse is a specialized intercellular junction that operates nearly autonomously to allow rapid, specific, and local communication between neurons. Focusing our attention on the presynaptic terminal, we review the current understanding of how synaptic morphology is maintained and then the mechanisms in synaptic vesicle exocytosis and recycling.

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Cite This Study

Murthy et al. (2003) studied this question.

synapsesocial.com/papers/6a20f0d5a4e184e828180ce4https://doi.org/10.1146/annurev.neuro.26.041002.131445
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Piccolo, a novel 420 kDa protein associated with the presynaptic cytomatrix.1996 · 181 citations
  2. 2Currents through the fusion pore that forms during exocytosis of a secretory vesicle1987 · 432 citations
  3. 3Functional Interaction of the Active Zone Proteins Munc13-1 and RIM1 in Synaptic Vesicle Priming2001 · 439 citations
  4. 4Endophilin Mutations Block Clathrin-Mediated Endocytosis but Not Neurotransmitter Release2002 · 341 citations
  5. 5The SAD-1 Kinase Regulates Presynaptic Vesicle Clustering and Axon Termination2001 · 188 citations