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June 4, 2026Algorithms0 citationsOpen Access

LSF-Mamba: A Lightweight Skin Lesion Segmentation Network with Local Structural Compensation and Frequency-Domain Residual Supplementation

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JZJ ZhangWLWei LiangGQGuanqiu Qi

Key Points

  • This research aims to enhance skin lesion segmentation accuracy while reducing model complexity.
  • Proposed the LSF-Mamba framework integrating Local Context Recalibration and Frequency Residual Enhancement modules.
  • Utilized wavelet decomposition and gated residual injection for enhanced feature representation.
  • Conducted experiments on ISIC2017, ISIC2018, and PH2 datasets.
  • Achieved competitive performance with only 0.0491 million parameters and 0.028 billion FLOPs.
  • Improved completeness of lesion segmentation compared to existing methods.
  • Enhanced accuracy of boundary delineation for skin lesions.

Abstract

Accurate skin lesion segmentation remains a significant challenge for lightweight models, as they often struggle to effectively balance global context understanding with stable local structural representation. Shallow skip connections can introduce redundant background noise into the decoder, while lightweight Mamba-based backbones have limited ability to preserve two-dimensional local continuity during sequential scanning. Additionally, direct enhancement in the frequency domain may amplify high-frequency components that are irrelevant to lesion discrimination, thereby compromising representation stability. To address these issues, this paper proposes LSF-Mamba, a lightweight skin lesion segmentation framework that integrates spatial-domain local compensation and frequency-domain residual supplementation. Specifically, a Local Context Recalibration (LCR) module is designed to reinforce shallow structural features through local neighborhood aggregation and channel-wise recalibration. In parallel, a Frequency Residual Enhancement (FRE) module is introduced to selectively incorporate structure-aware multi-band information using locally aligned wavelet decomposition and gated residual injection. Extensive experiments on the ISIC2017, ISIC2018, and PH2 datasets demonstrate that the proposed method achieves competitive performance with only 0.0491 M parameters and 0.028 G FLOPs, while producing more complete lesion segmentation and more accurate boundary delineation.

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Cite This Study

Zhang et al. (2026) studied this question.

synapsesocial.com/papers/6a211763d499ed480b1703cdhttps://doi.org/10.3390/a19060444
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