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September 1, 1965Biochemical Journal198 citationsOpen Access

Specific Binding of Concanavalin A to Cross-Linked Dextran Gels

BAB.B.L. AgrawalIGIrwin Goldstein

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Abstract

Concanavalin A, a globulin found in the jack bean, agglutinates certain animal erythrocytes (Sumner Cifonelli, Montgomery Goldstein, Hollerman & Merrick, 1963,1965a). The interaction of concanavalin A with carbohydrates is very specific, formation of a visible precipitate occurring only with branched polysaccharides that contain CX-D-glucopyranosyl or x-D-mannopyranosyl resi- dues at non-reducing chain ends (Goldstein et al.

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Agrawal et al. (1965) studied this question.

synapsesocial.com/papers/6a219517f6aa648d3a582bcbhttps://doi.org/10.1042/bj0960023c
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1SPECIFIC FRACTIONATION OF A POPULATION OF ANTIDEXTRAN MOLECULES WITH COMBINING SITES OF VARIOUS SIZES1962 · 80 citations
  2. 2Identification of Hemagglutinin of Jack Bean with Concanavalin A1936 · 454 citations
  3. 3Protein-Carbohydrate Interaction. II. Inhibition Studies on the Interaction of Concanavalin A with Polysaccharides*1965 · 852 citations
  4. 4Protein-carbohydrate interaction I. The interaction of polysaccharides with concanavalin A1965 · 353 citations
  5. 5The Lectins: Their Present Status*1963 · 194 citations