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Macrophage polarization refers to how macrophages have been activated at a given point in space and time. Polarization is not fixed, as macrophages are sufficiently plastic to integrate multiple signals, such as those from microbes, damaged tissues, and ...Read More
Thomas H. Hostetter (1995) studied this question. Macrophage polarization is a dynamic, plastic process that allows macrophages to integrate multiple signals from microbes and damaged tissues.