International audience
“In this issue of the European Heart Journal, Peikert et al., have used data from the PARAGON-HF trial to explore the prevalence of obesity and its prognostic associations in a HFpEF/HFmrEF population, using both the BMI and WHtR. The authors found that although about half of the patients included in the trial were considered obese based on a BMI ≥ 30 kg/m2, nearly every patient (96%) had central adiposity based on a WHtR ≥0.5. Furthermore, both increasing BMI and increasing WHtR were associated with higher risk of total HF hospitalizations, but these events were more closely related to WHtR than to BMI.”
Marques et al. (2025) studied this question. Obesity and metrics of central adiposity were evaluated for their prognostic significance in patients with heart failure with preserved and mildly reduced ejection fraction.