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January 5, 2018The Indian Journal of Pediatrics41 citationsOpen Access

Global Polio Eradication – Way Ahead

SBSunil BahlPBPankaj BhatnagarRSRoland W. Sutter

Key Result

Global polio eradication requires sustained efforts to interrupt wild poliovirus transmission in remaining endemic countries, manage vaccine-derived polioviruses, and transition from oral to inactivated vaccines.

PICO

P
Population
Poliomyelitis
I
Intervention / Comparator
Polio eradication strategies (OPV and IPV)

Limitations

  • Challenges in accessing marginal populations in security-compromised areas
  • Emergence and circulation of vaccine-derived polioviruses
  • Global shortages of inactivated poliovirus vaccine (IPV)
  • Prolonged poliovirus excretion in immunodeficient individuals

Abstract

In 1988, the World Health Assembly resolved to eradicate poliomyelitis by the year 2000. Although substantial progress was achieved by 2000, global polio eradication proved elusive. In India, the goal was accomplished in 2011, and the entire South-East Asia Region was certified as polio-free in 2014. The year 2016 marks the lowest wild poliovirus type 1 case count ever, the lowest number of polio-endemic countries (Afghanistan, Nigeria and Pakistan), the maintenance of wild poliovirus type 2 eradication, and the continued absence of wild poliovirus type 3 detection since 2012. The year also marks the Global Polio Eradication Initiative (GPEI) moving into the post-cessation of Sabin type 2, after the effort of globally synchronized withdrawal of Sabin type 2 poliovirus in April 2016. Sustained efforts will be needed to ensure polio eradication is accomplished, to overcome the access and security issues, and continue to improve the quality and reach of field operations. After that, surveillance (the "eyes and ears") will move further to the center stage. Sensitive surveillance will monitor the withdrawal of all Sabin polioviruses, and with facility containment, constitute the cornerstones for eventual global certification of wild poliovirus eradication. An emergency response capacity is essential to institute timely control measures should polio still re-emerge. Simultaneously, the public health community needs to determine whether and how to apply the polio-funded infrastructure to other priorities (after the GPEI funding has stopped). Eradication is the primary goal, but securing eradication will require continued efforts, dedicated resources, and a firm commitment by the global public health community.

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Cite This Study

Bahl et al. (2018) conducted a review in Poliomyelitis. Polio eradication strategies (OPV and IPV) was evaluated. Global polio eradication requires sustained efforts to interrupt wild poliovirus transmission in remaining endemic countries, manage vaccine-derived polioviruses, and transition from oral to inactivated vaccines.

synapsesocial.com/papers/6a2250dc4ae3d51087970fa8https://doi.org/10.1007/s12098-017-2586-8
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