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June 5, 2026International Journal of Colorectal Disease0 citationsOpen Access

Management of bowel dysfunction after pelvic surgery for endometriosis

JMJacopo MartellucciSOSimone Orlandi

Key Points

  • The aim is to summarize the complex causes and current treatments for bowel dysfunction following surgery for endometriosis.
  • Conducted a structured narrative review of studies published between 2000 and 2025.
  • Focused on postoperative functional outcomes and effective treatments.
  • Extrapolated evidence from related conditions like LARS and neurogenic bowel dysfunction.
  • Identified factors such as visceral hypersensitivity and surgical disruption of pelvic autonomic nerves contributing to dysfunction.
  • Dietary changes and medications serve as first-line treatments but are often inadequate for severe symptoms.
  • Emerging therapies include transanal irrigation for mechanical emptying and sacral neuromodulation for sensorimotor disorders.

Abstract

INTRODUCTION: Bowel dysfunction is a common and debilitating condition affecting patients with endometriosis. Despite the extent of surgery, symptoms may persist or arise, often overlapping with low anterior resection syndrome (LARS) or irritable bowel syndrome (IBS) typical features. This review aims to summarize the multifactorial pathophysiology and current therapeutic options for postoperative bowel dysfunction after endometriosis surgery. METHODS: A structured narrative review was conducted through a comprehensive search for studies published between 2000 and 2025. Inclusion criteria focused on postoperative functional outcomes and treatments (medical, rehabilitative and interventional) effectiveness. The available evidence is limited and largely extrapolated from related conditions such as LARS and neurogenic bowel dysfunction. RESULTS: The complex pathophysiology of postoperative dysfunction involves preoperative visceral hypersensitivity, surgical disruption of pelvic autonomic nerves, reduced rectal compliance, and pelvic floor dyssynergia. While dietary interventions (e.g., low-FODMAP diet) and pharmacological treatments (laxatives, antidiarrheals, or neuromodulators) serve as first-line therapies, they are often insufficient for severe symptoms. Emerging evidence supports the use of transanal irrigation (TAI) for mechanical emptying and sacral neuromodulation (SNM) for refractory sensorimotor disorders. Functional rehabilitation, including pelvic floor physiotherapy and manual therapy, represents a further opportunity to influence specific symptoms. CONCLUSIONS: Postoperative bowel dysfunction in endometriosis management requires a transition from rigid treatment protocols to a multidisciplinary, symptom-oriented approach. The support of specialized nursing, physiotherapy, and advanced interventions like TAI and SNM is essential. Future prospective studies using standardized outcome measures are needed to better define these therapeutic pathways and improve patient quality of life.

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Cite This Study

Martellucci et al. (2026) studied this question.

synapsesocial.com/papers/6a2268d7763171746d5475fahttps://doi.org/10.1007/s00384-026-05163-1
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