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August 1, 1988Archives of Internal Medicine221 citations

Selective Screening for Abdominal Aortic Aneurysms With Physical Examination and Ultrasound

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FLFrank A. Lederle

Key Result

Screening with physical examination and ultrasound detected previously unsuspected abdominal aortic aneurysms in 9% (95% CI 4.7-13.3%) of high-risk men aged 60 to 75 years.

Study Design

Type

Cross-Sectional (n=201)

Structured PICO

Does selective screening with physical examination and ultrasound effectively detect previously unsuspected abdominal aortic aneurysms in high-risk older men?

P
Population
201 men aged 60 to 75 years with hypertension and/or coronary artery disease screened for abdominal aortic aneurysm.
E
Exposure
Selective screening for abdominal aortic aneurysms using physical examination (abdominal palpation) and abdominal ultrasound.
O
Outcome
Prevalence of previously unsuspected abdominal aortic aneurysms.surrogate

Selective screening with ultrasound in high-risk older men (aged 60-75 with hypertension or CAD) yields a high prevalence (9%) of previously unsuspected abdominal aortic aneurysms.

Abstract

Abdominal aortic aneurysm (AAA) is an important cause of preventable death in older persons. Persistently high rupture mortality rates indicate that these deaths can be prevented only by early detection and treatment of AAA. In an effort to develop an effective and efficient program of AAA detection, we selectively screened a high-risk population. Men aged 60 to 75 years with hypertension and/or coronary artery disease were randomly selected from a general medicine clinic and screened with physical examination and ultrasound. Eighteen previously unsuspected aneurysms, 3.6 to 5.9 cm in size (mean, 4.4 cm), were detected in 201 patients, for a prevalence of 9% (95% confidence interval: 4.7% to 13.3%). The specificity and positive predictive value of ultrasound were each 100%. Abdominal palpation detected only half of these aneurysms, but missed none in patients with an abdominal girth less than 100 cm (n = 6). This degree of sensitivity did not occur with "routine" examinations and requires that the examination be directed specifically toward AAA detection. We conclude that undiagnosed AAAs are common in this large subgroup of the clinic population, that ultrasound is an excellent screening test for AAAs, and that physical examination may be adequate for screening thin patients. We recommend that every two or three years persons over the age of 50 years undergo careful abdominal palpation aimed at detecting AAAs, as part of the periodic health examination. We further recommend that obese older men at high risk for AAA have at least one-time screening with abdominal ultrasound, regardless of findings on physical examination.

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Cite This Study

Frank A. Lederle (1988) conducted a cross-sectional in Abdominal aortic aneurysm (n=201). Physical examination and ultrasound screening was evaluated on Prevalence of previously unsuspected abdominal aortic aneurysms (95% CI 4.7-13.3). Screening with physical examination and ultrasound detected previously unsuspected abdominal aortic aneurysms in 9% (95% CI 4.7-13.3%) of high-risk men aged 60 to 75 years.

synapsesocial.com/papers/6a22961837cd05c4adcd3c18https://doi.org/10.1001/archinte.1988.00380080049015
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