Systolic blood pressure (P<0.001), male sex, total to high-density lipoprotein cholesterol ratio, and age independently predicted carotid intima-media thickness in young adults.
Observational (n=1,203)
Systolic blood pressure, age, male sex, and total-to-HDL cholesterol ratio are independent predictors of carotid intima-media thickness in young adults.
p-value: p=<.001
The authors' aim was to determine reference values and predictors for carotid intima-media thickness (CIMT) in the Bogalusa Heart Study. Carotid ultrasound images from 1203 young adults (mean age 36 years; 30% black, 43% male) were reviewed. Age-, sex-, and race-specific CIMT percentiles were estimated using multivariable regression. Nomograms of CIMT quartiles for persons aged 25 to 40 years are provided in 5-year increments. CIMT was thickest in the carotid bulb and increased linearly with age, most rapidly in the bulb. With age, composite CIMT increased most slowly in white women and more rapidly in white men and black women. Systolic blood pressure (P<.001) was the strongest predictor of composite CIMT. Male sex, total to high-density lipoprotein cholesterol ratio, and age independently predicted CIMT in all segments. This report may be used to help plan epidemiologic investigations and clinical trials investigating atherosclerosis and its changes with interventions.
Tzou et al. (2007) reported an observational. Cardiovascular risk factors (systolic blood pressure, age, sex, cholesterol) was evaluated on Carotid intima-media thickness (CIMT) (p=<.001). Systolic blood pressure (P<0.001), male sex, total to high-density lipoprotein cholesterol ratio, and age independently predicted carotid intima-media thickness in young adults.
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