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January 22, 2010Organic Letters114 citationsOpen Access

Quorum-Sensing-Regulated Bactobolin Production by Burkholderia thailandensis E264

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MSMohammad R. SeyedsayamdostJCJosephine R. ChandlerJBJoshua A. V. Blodgett

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Abstract

Bacterial acyl-homoserine lactones upregulated an uncharacterized gene cluster (bta) in Burkholderia thailandensis E264 to produce an uncharacterized polar antibiotic. The antibiotic is identified as a mixture of four bactobolins. Annotation of the bta cluster allows us to propose a biosynthetic scheme for bactobolin and reveals unusual enzymatic reactions for further study.

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Cite This Study

Seyedsayamdost et al. (2010) studied this question.

synapsesocial.com/papers/6a22bd2360296ba93ed2ce32https://doi.org/10.1021/ol902751x
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