Why the study?
Does pulmonary hypertension increase the risk of heart failure hospitalization and mortality in African Americans with chronic kidney disease?
Population
408 African American participants with chronic kidney disease and available echocardiogram-derived pulmonary…
Comparison
Pulmonary hypertension (PASP >35 mm Hg) vs No pulmonary hypertension (PASP ≤35 mm Hg)
Design
Cohort
Key result
Among African Americans with chronic kidney disease, pulmonary hypertension was associated with a higher risk of heart failure hospitalization (HR 2.37; 95% CI 1.15-4.86).
Authors
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PH may identify higher-risk African American CKD patients for surveillance; leaves open whether it is a modifiable HF target.
Cohort (n=408)
Does pulmonary hypertension increase the risk of heart failure hospitalization and mortality in African Americans with chronic kidney disease?
Hazard Ratio: 2.37 (95% CI 1.15–4.86)
In African Americans with chronic kidney disease, the presence of pulmonary hypertension is associated with a significantly higher risk of heart failure hospitalization and mortality.
Selvaraj et al. (2017) conducted a cohort in Chronic kidney disease (n=408). Pulmonary hypertension vs. No pulmonary hypertension was evaluated on Heart failure hospitalization (HR 2.37, 95% CI 1.15-4.86). Among African Americans with chronic kidney disease, pulmonary hypertension was associated with a higher risk of heart failure hospitalization (HR 2.37; 95% CI 1.15-4.86).