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July 1, 2014Antimicrobial Agents and Chemotherapy240 citationsOpen Access

Preliminary Study of Colistin versus Colistin plus Fosfomycin for Treatment of Carbapenem-Resistant Acinetobacter baumannii Infections

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RSRujipas SirijatuphatVTVisanu Thamlikitkul

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Abstract

Ninety-four patients infected with carbapenem-resistant Acinetobacter baumannii were randomized to receive colistin alone or colistin plus fosfomycin for 7 to 14 days. The patients who received combination therapy had a significantly more favorable microbiological response and a trend toward more favorable clinical outcomes and lower mortality than those who received colistin alone. (This study has been registered at ClinicalTrials.gov under registration no. NCT01297894.).

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Sirijatuphat et al. (2014) studied this question.

synapsesocial.com/papers/6a23a006003b3cd7fea5f87ahttps://doi.org/10.1128/aac.02435-13
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