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July 1, 1992Archives of Surgery205 citations

End-Diastolic Volume

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LDLawrence N. DiebelRELX Group (Netherlands)

Key Result

Right ventricular end-diastolic volume index (RVEDVI) correlated better with cardiac index (r=0.61) than pulmonary artery wedge pressure (r=0.42) and accurately predicted fluid responsiveness.

Study Design

Type

Observational (n=29)

Structured PICO

Does RVEDVI predict preload recruitable increases in cardiac output better than PAWP in critically ill patients?

P
Population
29 critically ill patients undergoing hemodynamic monitoring to evaluate preload status.
E
Exposure
Measurement of right ventricular end-diastolic volume index (RVEDVI)
C
Comparator
Measurement of pulmonary artery wedge pressure (PAWP)
O
Outcome
Correlation with cardiac index (CI) and prediction of preload recruitable increases in cardiac output (response to fluid challenge)surrogate

RVEDVI is a more accurate predictor of preload recruitable increases in cardiac output than PAWP in critically ill patients.

Abstract

The relative value of pulmonary artery wedge pressure (PAWP) and right ventricular end-diastolic volume index (RVEDVI) as a reflection of the preload status of the critically ill was determined in 29 patients. Regression analysis of 131 hemodynamic studies demonstrated that cardiac index (CI) correlated better with RVEDVI (r = .61) than did PAWP (r = .42). Comparisons of PAWP and RVEDVI showed that possible misleading information concerning filling volume was provided by the PAWP at some time in 15 (52%) of these patients. In 15 patients given 22 fluid challenges, patients with a high PAWP (greater than or equal to 18 mm Hg) "responded" with a rise in CI more frequently than did patients with a low PAWP (less than 12 mm Hg). However, all eight patients with a RVEDVI less than 90 mL/m2 responded with a rise in CI, but all seven patients with a RVEDVI greater than or equal to 139 mL/m2 failed to respond. Thus, RVEDVI more accurately predicted preload recruitable increases in cardiac output.

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Cite This Study

Lawrence N. Diebel (1992) conducted an observational in Critically ill (n=29). Right ventricular end-diastolic volume index (RVEDVI) vs. Pulmonary artery wedge pressure (PAWP) was evaluated on Correlation with cardiac index (CI). Right ventricular end-diastolic volume index (RVEDVI) correlated better with cardiac index (r=0.61) than pulmonary artery wedge pressure (r=0.42) and accurately predicted fluid responsiveness.

synapsesocial.com/papers/6a23a0b296b50e6ae79ef1c2https://doi.org/10.1001/archsurg.1992.01420070081015
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