Population
Human kidney cortex extract
Comparison
Extraction in low ionic strength buffer with… vs Extraction without protease inhibitors, multiple…
Design
Preclinical
Authors
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Hypothesis-generating for prorenin as kidney renin precursor; leaves open its relation to plasma forms.
The identification of a 58,000-dalton form of renin in human kidney cortex suggests it may be a biosynthetic precursor to the smaller circulating plasma renin.
Slater et al. (1978) studied this question.