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December 31, 2020Indonesian Journal of Pharmaceutical and Clinical Research5 citationsOpen Access

Effect of Adherence with Clinical Outcomes and Quality of Life Primary Hypertension Patients in Pharmacy

DHDumartina HutaurukKKKhairunnisa KhairunnisaWWWiryanto Wiryanto

Key Result

Medication adherence in primary hypertension patients was significantly correlated with clinical outcomes (r=-0.745, p<0.05) and quality of life (r=0.554, p<0.05).

Study Design

Type

Cross-Sectional (n=60)

Multicenter

No

Structured PICO

Does medication adherence correlate with blood pressure and quality of life in primary hypertension patients?

P
Population
60 primary hypertension patients (60% female) evaluated at a single pharmacy in Medan, Indonesia.
E
Exposure
Medication adherence (assessed via MMAS-8 questionnaire)
O
Outcome
Clinical outcomes (blood pressure) and quality of life (assessed via EQ-5D-3L questionnaire)surrogate

Medication adherence is strongly correlated with improved blood pressure control and moderately correlated with better quality of life in primary hypertension patients.

Main Result

Effect estimate: r= -0.745

p-value: p=<0.05

Abstract

This study aimed to examine the effect of adherence to clinical outcomes and the quality of life of primary hypertension patients in pharmacy. The studywas conducted cross sectionally involved 60 patients at one of the pharmacies in Medan, Indonesia. Adherence was obtained in the form of adherence levels measured using the MMAS-8 questionnaire, clinical outcomes assessed by measuring a patient's blood pressure, and quality of life assessed using the EQ-5D-3L questionnaire. Then the data were analyzed using the Spearmen rho test. Patients who participated in the study consisted of 24 men and 36 women. Almost patient has low adherence with blood pressure mean of 156/ 90 mmHg. The patient's quality of life was 77.7%. Adherence has a significant relationship to clinical outcomes (p<0.05) with a strong correlation of r= -0.745. Adherence has a relationship to quality of life (p<0.05) with moderate correlation r= 0.554. This study concluded that adherence has a correlation with clinical outcomes and the quality of life of primary hypertension patients.

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Cite This Study

Hutauruk et al. (2020) conducted a cross-sectional in Primary hypertension (n=60). Medication adherence was evaluated on Correlation between adherence and clinical outcomes (blood pressure) (r= -0.745, p=<0.05). Medication adherence in primary hypertension patients was significantly correlated with clinical outcomes (r=-0.745, p<0.05) and quality of life (r=0.554, p<0.05).

synapsesocial.com/papers/6a2419f4637bef72baab37cahttps://doi.org/10.32734/idjpcr.v3i2.5129
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The Impact of Medication Adherence on Quality of Life in Hypertensive Patients: A Cross-Sectional Analysis2025
  2. 222 QUALITY OF LIFE AND FUNCTIONAL CAPACITY IMPROVEMENT FOLLOWING MEDICATION ADHERENCE IN LONG-STANDING HYPERTENSION2018
  3. 3Evaluation of Correlation Between Adherence to the Treatment of Hypertansive Patients and Their Life Quality2018 · 30 citations
  4. 4A Study on Impact of Clinical Pharmacist Interventions on Medication Adherence and Quality of Life in Rural Hypertensive Patients2012 · 62 citations
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