Two different definitions of type 2 myocardial infarction were evaluated for their effect on incidence and prognosis in 4,015 consecutive patients presenting with symptoms suggestive of MI.
Observational (n=4,015)
Does the definition of Type 2 Myocardial Infarction affect its incidence, treatment, and event-related mortality in patients presenting with symptoms suggestive of myocardial infarction?
The specific diagnostic definition applied to Type 2 Myocardial Infarction significantly impacts its reported incidence and clinical outcomes.
BACKGROUND: Uncertainties regarding the most appropriate definition and treatment of type 2 myocardial infarction (T2MI) due to supply-demand mismatch have contributed to inconsistent adoption in clinical practice. OBJECTIVES: This study sought a better understanding of the effect of the definition of T2MI on its incidence, treatment, and event-related mortality, thereby addressing an important unmet clinical need. METHODS: The final diagnosis was adjudicated in patients presenting with symptoms suggestive of myocardial infarction by 2 independent cardiologists by 2 methods: 1 method required the presence of coronary artery disease, a common interpretation of the 2007 universal definition (T2MI RESULTS: Overall, 4,015 consecutive patients were adjudicated. The incidence of T2MI based on the T2MI CONCLUSIONS: T2MI
Nestelberger et al. (2017) conducted an observational in Type 2 myocardial infarction (n=4,015). Definition of T2MI requiring coronary artery disease vs. Alternative definition of T2MI was evaluated on Incidence of T2MI. Two different definitions of type 2 myocardial infarction were evaluated for their effect on incidence and prognosis in 4,015 consecutive patients presenting with symptoms suggestive of MI.