PulseExploreJournal ClubDebatesTrendingResearchersJournals
Instagram
HomeExploreJournal ClubTrending
Synapse
⌘+K
Synapse
June 7, 2026OncoTargets and Therapy0 citationsOpen Access

lncRNA FBXL19-AS1 Regulates Osteosarcoma Cell Proliferation, Migration and Invasion by Sponging miR-346 Retraction

RPRunsang PanZHZhixu HeWRWanyuan Ruan

Key Points

  • Investigate the role of lncRNA FBXL19-AS1 in regulating osteosarcoma cell behavior through its interaction with miR-346.
  • Article retracted due to data integrity issues identified in figures.
  • Concerns raised regarding image similarities in multiple assay panels.
  • Journal and Publisher conducted an investigation to confirm the issues.
  • Confidence in the reported conclusions has been lost due to the identified data integrity concerns.
  • Retraction remains to maintain the scholarly record with appropriate warnings.

Abstract

Pan RS, He ZX, Ruan WY, et al. Onco Targets Ther. 2018;11:84098420. https://doi.org/10.2147/OTT.S160963 We, the Editors and Publisher of the journalOncoTargets and Therapy, have retracted the published article. Afterpublication, concerns have been raisedby a third partyin 2026about the integrity of the data inFigures 2, 4, 6, and 7ofthe article.The authors then contacted the publisher to request a correction to the article. Further investigation conducted by the Journal and Publisherconfirmed the following: unexpected similarities between the image panels for the colony formation assays in Figures 2B and 6B, which are representative of different samples and treatment conditions; unexpected similarities between the image panels for the transwell assays in Figures 4E and 4G, which are representative of different samples and treatment conditions; unexpected similarities between the image panels between Figures 7E and 7G, which are representative of different samples and treatment conditions. Given the extent of image integrity concerns in the figures published, the Journal and Publisher no longer have confidence in the reported conclusions. Therefore, we are retracting the article. The corresponding author listed in this publication has been informed. We have been informed in our decision-making by oureditorial policies and the COPE guidelines. The retracted article will remain online tomaintainthe scholarly record, but it will be digitally watermarked on each page as Retracted.

Ask AI
Helpful
Bookmark
Share
View Full Paper

Cite This Study

Pan et al. (2026) studied this question.

synapsesocial.com/papers/6a250a717def13d035e1a9dchttps://doi.org/10.2147/ott.s629832
Ask AI
Helpful
Bookmark
Share
View Full Paper