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June 10, 2026European Geriatric Medicine1 citationsOpen Access

Prevalence of pre-frailty and frailty and their association with postoperative hospital days in older adults referred for elective orthopaedic surgery

MFMarie Linderup FunckLKLotte Sejr KirringASAnne Mette Schmidt

Key Result

Pre-frailty in older adults referred for elective orthopaedic surgery was associated with an adjusted mean increase of 0.5 postoperative hospital days compared to non-frail patients.

Key Points

  • This research aims to examine the prevalence of pre-frailty and frailty in older adults scheduled for elective orthopedic surgery and their relationship with postoperative complications.
  • Included individuals aged 65+ referred for elective shoulder, knee, hip, or spine surgery from April to July 2022.
  • Health status was assessed preoperatively using the Multidimensional Prognostic Index.
  • Postoperative hospital data were obtained from a regional database.
  • 26% of participants were classified as pre-frail and 4% as moderately frail.
  • Pre-frailty was associated with an increased number of hospital days post-surgery compared to non-frail individuals.
  • Moderate frailty was also linked to a greater number of hospital days within 90 days after surgery.

Study Design

Type

Cohort (n=519)

Multicenter

No

Structured PICO

Is pre-frailty and frailty associated with increased postoperative hospital days in older adults referred for elective orthopaedic surgery?

P
Population
519 older adults aged 65 years or older referred for elective orthopaedic surgery, assessed for frailty and followed for 90 days post-surgery.
E
Exposure
Pre-frailty and moderate frailty (assessed preoperatively using the record-based Multidimensional Prognostic Index)
C
Comparator
Non-frail persons
O
Outcome
Number of days spent in the hospital within 90 days after surgery

More than 25% of older adults referred for elective orthopaedic surgery are pre-frail or frail, which is associated with increased postoperative hospital days.

Main Result

Mean Difference: 0.5 (95% CI 0.2–0.8)

Absolute Event Rate: 2.8% vs 2.2%

p-value: p=<0.001

Limitations

  • Small number of cases in spine and shoulder surgery subgroups
  • ADL and IADL data may have been difficult to extract reliably from the EMRs, potentially underestimating frailty prevalence
  • Did not adjust for variables such as social position
  • Did not include data on medications, outpatient visits, or general practice contacts
  • Specific outcomes like mortality, prolonged wound healing, delirium, and infections were not examined

Abstract

PURPOSE: The aim of this study was to investigate the prevalence of pre-frailty and frailty among older persons referred for elective orthopaedic surgery and determine whether frailty was associated with the occurrence of postoperative complications, measured as the number of days spent in the hospital within 90 days after surgery. METHODS: Between April 1 and July 31, 2022, we consecutively included individuals aged 65 years or older who were referred for elective shoulder, knee, hip, or spine surgery at a centre for elective surgery. Health status was assessed preoperatively using the record-based Multidimensional Prognostic Index, based on data extracted from the electronic medical record by a geriatrician. Postoperative hospital data were obtained from the Business Intelligence Data Warehouse of the Central Denmark Region. RESULTS: A total of 519 persons were included, with a mean age of 75.2 years (SD 5.9), and 56% were females. The majority of the persons were referred for elective hip (41%) or knee (37%) arthroplasty. Preoperatively, 26% of the persons were classified as pre-frail and 4% as moderately frail, while none were severely frail. Pre-frailty and moderate frailty were associated with a greater number of hospital days within 90 days post-surgery compared with non-frail persons. CONCLUSION: More than one in four older persons aged 65 + referred for elective orthopaedic surgery are pre-frail or moderate frail. Identifying this vulnerability is essential for optimizing care across healthcare settings and professions, with the goal of preventing postoperative complications.

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Cite This Study

Funck et al. (2026) conducted a cohort in Elective orthopaedic surgery (n=519). Pre-frailty vs. Non-frail was evaluated on Mean number of postoperative hospital days (MD 0.5, 95% CI 0.2-0.8, p=<0.001). Pre-frailty in older adults referred for elective orthopaedic surgery was associated with an adjusted mean increase of 0.5 postoperative hospital days compared to non-frail patients.

synapsesocial.com/papers/6a28fecb6f82f25be989c03ahttps://doi.org/10.1007/s41999-026-01515-w
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