Exercise rehabilitation therapy significantly improved cardiopulmonary function, cardiac pumping function, NT-proBNP levels, and quality of life in elderly patients with chronic heart failure (P<0.05).
RCT (n=92)
Random number table
No
Does exercise rehabilitation therapy improve cardiopulmonary function, cardiac pumping function, NT-proBNP, and quality of life in elderly patients with chronic heart failure?
Exercise rehabilitation therapy added to routine medical care significantly improves exercise capacity, cardiac function, biomarker levels, and quality of life in elderly patients with chronic heart failure.
p-value: p=<0.05
摘要： 目的 探讨运动康复疗法对老年慢性心力衰竭（CHF）患者心肺功能、心脏泵血功能、B型钠尿肽前体（NT-proBNP）及生活质量的影响。 方法 选取2023年3月—2024年1月齐齐哈尔医学院附属第一医院收治的92例CHF患者为研究对象，采用随机数表法分为康复组与对照组，各46例。对照组接受常规药物干预，康复组在对照组基础上增加运动康复疗法。干预3个月后，比较两组无氧阈（AT）、最大摄氧量（VO2max）、每搏氧耗量（O2pulse）、NT-proBNP、左心室射血分数（LVEF）、左心室舒张末期容积（LVEDV）、左心室收缩末期容积（LVESV）及明尼苏达评分（MLHFQ）。 结果 干预前，两组AT、VO2max、O2pulse比较，差异无统计学意义（P>0.05）；干预后，康复组AT、VO2max、O2pulse均高于干预前，且康复组AT、VO2max、O2pulse均显著高于对照组（PP>0.05）。干预前，两组LVEF、LVESV、LVEDV比较，差异无统计学意义（P>0.05）；干预后，康复组LVEF高于干预前，LVESV、LVEDV均低于干预前，且康复组LVEF高于对照组，LVESV、LVEDV均低于对照组（PP>0.05）。干预前，两组NT-proBNP水平、MLHFQ评分比较，差异无统计学意义（P>0.05）；干预后，康复组NT-proBNP水平、MLHFQ评分均低于干预前，且康复组NT-proBNP水平、MLHFQ评分均低于对照组（PP>0.05）。 结论 运动康复疗法能有效改善老年CHF患者的心肺功能指标、心脏泵血功能指标及NT-proBNP水平，提高患者生活质量。
QI et al. (2026) conducted an RCT in Chronic Heart Failure (n=92). Exercise rehabilitation therapy vs. Conventional drug intervention was evaluated on Cardiopulmonary function, cardiac pumping function, NT-proBNP, and quality of life (p=<0.05). Exercise rehabilitation therapy significantly improved cardiopulmonary function, cardiac pumping function, NT-proBNP levels, and quality of life in elderly patients with chronic heart failure (P<0.05).