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June 14, 2026Journal of Critical Care0 citationsOpen Access

Implementation and evaluation of the multidisciplinary “ABCDEF of sleep” protocol in Brazilian intensive care units: A quasi-experimental study. Results of a two-phase

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LDLaura DrehmerFNFelippe Leopoldo Dexheimer NetoAFAnielle Ferrazza

Key Points

  • The study aimed to evaluate the effectiveness of a multidisciplinary sleep protocol in improving sleep quality for critically ill patients in ICUs.
  • Conducted as a multicenter quasi-experimental before-after study in two Brazilian ICUs.
  • Included adult patients with an ICU stay of ≥2 nights, using RCSQ and SICUQ for sleep assessment.
  • Implemented the ABCDEF of Sleep protocol following baseline assessments.
  • The aggregated 3-night RCSQ score showed no significant difference (p = 0.31) between control and intervention groups.
  • Higher RCSQ scores were observed on the second night for the intervention group (p = 0.008).
  • The intervention improved perceived sleep quality and reduced environmental disturbances (p ≤ 0.001), with no effects on overall clinical outcomes.

Abstract

Introduction Sleep disruption is common in intensive care units (ICUs) and is associated with adverse outcomes. We evaluated whether a multidisciplinary sleep protocol improves subjective sleep quality in critically ill patients. Methods This multicenter quasi-experimental before–after study (2022–2024) was conducted in two Brazilian ICUs. Adult patients with an ICU stay of ≥2 nights were included. Sleep was assessed using the Richards–Campbell Sleep Questionnaire (RCSQ) and the Sleep in the ICU Questionnaire (SICUQ). Following baseline assessment, structured training and a multifaceted “ABCDEF of Sleep” protocol were implemented. The primary outcome was the global RCSQ score; secondary outcomes included SICUQ domains and clinical outcomes. Results A total of 112 patients were included (control = 61; intervention = 51). The primary outcome (aggregated 3-night RCSQ score) did not differ between groups ( p = 0.31). In per-night analyses, RCSQ scores were higher on the second night in the intervention group ( p = 0.008), with no differences on nights 1 or 3. The intervention improved perceived sleep quality and reduced environmental disturbances ( p ≤ 0.001), without effects on mortality, mechanical ventilation, or length of stay. Family-reported sleep perception did not differ between groups. Conclusions A pragmatic sleep protocol improved subjective sleep quality and reduced environmental disturbances in ICU patients, but did not impact major clinical outcomes. Larger studies using objective measures are needed.

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Cite This Study

Drehmer et al. (2026) studied this question.

synapsesocial.com/papers/6a2e479db1cc60ccdea8c216https://doi.org/10.1016/j.jcrc.2026.155649
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