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June 16, 2026Clinical Cardiology1 citationsOpen Access

Impact of Cardiovascular Specialty Care Based on the Humanistic Concept on Medication Adherence, Glycolipid Metabolism Parameters, and Quality of Life in High‐Risk Cardiovascular Patients With Lipid Management

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MWMin WangYXYonghui XuHWH Y Wang

Key Result

Humanistic concept-based specialty nursing was associated with significantly higher total medication adherence compared to conventional care (95.00% vs. 81.82%, p<0.05).

Key Points

  • This study examines how humanistic concept-based nursing affects adherence to medications and life quality in high-risk cardiovascular patients.
  • Retrospective analysis of 115 high-risk cardiovascular patients admitted from December 2023 to November 2024.
  • Patients divided into control (conventional care) and observation (humanistic specialty nursing) groups.
  • Outcomes measured included medication adherence, glycolipid metabolism parameters, anxiety, self-management, and quality of life.
  • Observation group showed significantly higher medication adherence (95% vs. 81.82%, χ² = 4.973, p < 0.05).
  • Post-intervention, glycolipid metabolic indicators and anxiety scores were significantly lower in the observation group (p < 0.05).
  • Self-management and quality of life scores were significantly improved in all domains for the observation group (p < 0.05).

Study Design

Type

Cohort (n=115)

Structured PICO

Does cardiovascular specialty nursing based on the humanistic concept improve medication adherence, glycolipid metabolism parameters, and quality of life in high-risk cardiovascular patients undergoing lipid management?

P
Population
115 high-risk cardiovascular patients undergoing lipid management, evaluated retrospectively.
E
Exposure
Cardiovascular specialty nursing based on the humanistic concept
C
Comparator
Conventional care
O
Outcome
Medication adherence assessed by the Morisky Medication Adherence Scale (MMAS-8)patient reported

Cardiovascular specialty nursing based on the humanistic concept improves medication adherence, metabolic parameters, and quality of life in high-risk cardiovascular patients.

Main Result

Absolute Event Rate: 95% vs 81.82%

p-value: p=<0.05

Abstract

OBJECTIVE: To investigate the effects of cardiovascular specialty nursing based on the humanistic concept on medication adherence, glycolipid metabolism parameters, psychological status, self-management ability, and quality of life in high-risk cardiovascular patients undergoing lipid management. METHODS: In this retrospective study, 115 high-risk cardiovascular patients admitted between December 2023 and November 2024 were selected from the medical record system and divided into two groups: a control group (n = 55, conventional care) and an observation group (n = 60, humanistic concept-based specialty nursing). Outcomes compared included medication adherence assessed by the Morisky Medication Adherence Scale (MMAS-8), glycolipid metabolism parameters including glycated hemoglobin (HbA1c), fasting plasma glucose (FPG), 2-h postprandial glucose (2hPG), triglycerides (TG), total cholesterol (TC), and low-density lipoprotein cholesterol (LDL-C), psychological status assessed by the State Anxiety Inventory (S-AI) and Trait Anxiety Inventory (T-AI) of the State-Trait Anxiety Inventory (STAI), self-management ability assessed by the Exercise of Self-Care Agency Scale (ESCA), and quality of life assessed by the Generic Quality of Life Inventory-74 (GQOLI-74). RESULTS: The observation group demonstrated significantly higher total medication adherence (95.00% vs. 81.82%, χ² = 4.973, p < 0.05). Post-intervention, all glycolipid metabolic indicators (HbA1c, FPG, 2hPG, TG, TC, LDL-C), as well as S-AI and T-AI anxiety scores, were significantly lower in the observation group compared with the control group (p < 0.05). Additionally, the observation group showed significantly higher scores in all ESCA self-management domains (self-concept, self-care responsibility, self-care skills, and health knowledge) and across all GQOLI-74 quality of life dimensions (material life, somatic function, social function, and psychological function) (p < 0.05). CONCLUSION: Cardiovascular specialty care based on the humanistic concept was associated with improvements in medication adherence, glycolipid metabolism parameters, psychological status, self-management ability, and quality of life in high-risk cardiovascular patients, suggesting high clinical applicability.

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Cite This Study

Wang et al. (2026) conducted a cohort in High-risk cardiovascular patients undergoing lipid management (n=115). Humanistic concept-based specialty nursing vs. Conventional care was evaluated on Total medication adherence (p=<0.05). Humanistic concept-based specialty nursing was associated with significantly higher total medication adherence compared to conventional care (95.00% vs. 81.82%, p<0.05).

synapsesocial.com/papers/6a31572eaf7cf7f8256b3da8https://doi.org/10.1002/clc.70290
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