Among 13 children hospitalized with EV-A71 neurologic disease, 12 developed meningitis, 9 developed encephalitis, and 3 developed acute flaccid myelitis, with all surviving.
Observational (n=13)
Testing nonsterile sites is crucial when enterovirus-associated central nervous system disease is suspected, as CSF testing is frequently negative.
In May 2018, the Colorado Department of Public Health and Environment was notified by Childrenâs Hospital Colorado of an increase in pediatric cases of meningitis and encephalitis, in which patients tested positive for enterovirus, which can cause hand, foot, and mouth disease and neurologic disease in children aged <5 years.
Messacar et al. (2018) conducted an observational in Enterovirus A71 Neurologic Disease (n=13). Enterovirus A71 infection was evaluated on Clinical manifestations and outcomes. Among 13 children hospitalized with EV-A71 neurologic disease, 12 developed meningitis, 9 developed encephalitis, and 3 developed acute flaccid myelitis, with all surviving.