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March 1, 2011Current Protocols in Mouse Biology278 citationsOpen Access

Echocardiography in Mice

SGShumin GaoDHDavid HoDVDorothy E. Vatner

Key Result

This review provides a practical guide to the applications and methods of echocardiography for evaluating cardiac systolic and diastolic function in mouse models of cardiovascular disease.

Structured PICO

P
Population
Mouse models of cardiovascular disease
E
Exposure
Echocardiography
O
Outcome
Evaluation of cardiac systolic and diastolic function

This review provides a practical guide for utilizing echocardiography to evaluate cardiovascular function in murine models.

Abstract

Murine models have been utilized with increasing frequency mainly due to availability of genetically engineered models. With advancement in high spatial and temporal resolution, echocardiography is used extensively for the evaluation of cardiovascular function in murine models of cardiovascular disease. This review summarizes the general applications and methods involved in echocardiography used to study mouse models for cardiovascular research, based on 20 years of experience in our laboratory. The goal of this article is to provide a practical guide to the use of echo techniques in mice to evaluate cardiac systolic and diastolic function.

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Gao et al. (2011) conducted a review in Cardiovascular disease in murine models. Echocardiography was evaluated. This review provides a practical guide to the applications and methods of echocardiography for evaluating cardiac systolic and diastolic function in mouse models of cardiovascular disease.

synapsesocial.com/papers/6a334987f992006f395e79c9https://doi.org/10.1002/9780470942390.mo100130
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