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April 1, 2017Cell Reports200 citationsOpen Access

Quantification of the Impact of the HIV-1-Glycan Shield on Antibody Elicitation

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TZTongqing ZhouNDNicole A. Doria‐RoseCCCheng Cheng

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Abstract

) proportional to the exponential of the protein-surface area accessible to antibody. Based on these high titers and exponential relationship, we propose site-selective deglycosylated trimers as priming immunogens to increase the frequency of site-targeting antibodies.

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Zhou et al. (2017) studied this question.

synapsesocial.com/papers/6a3387cb3b8943b2b5198f3ehttps://doi.org/10.1016/j.celrep.2017.04.013
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