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June 21, 2026OncoTargets and Therapy0 citationsOpen Access

MiR-153-3p Suppresses Cell Proliferation, Invasion and Glycolysis of Thyroid Cancer Through Inhibiting E3F3 Expression Retraction

XDXianzhao DengBGBomin GuoYFYouben Fan

Key Points

  • This article aimed to investigate the role of miR-153-3p in thyroid cancer cell proliferation, invasion, and glycolysis.
  • Publication retracted due to concerns about data integrity and similarities in reported flow cytometry and imaging data.
  • Figures were scrutinized for authenticity, leading to the retraction decision.
  • The article was retracted after confirming data integrity issues, compromising the reported findings.

Abstract

Deng X, Guo B, Fan Y. Onco Targets Ther.2021;14:519529. https://doi.org/10.2147/OTT.S267887 We, the Editors and Publisher of the journal OncoTargets and Therapy, have retracted the published article. After publication, concerns have been raised by a third party in 2023 about the integrity of the data in Figure 5 of the article. Further investigation conducted by the Journal and Publisher confirmed the following: Unexpected similarities between the flow cytometry data shown in Figure 2C and Figure 4D. Unexpected similarities between the cell migration and invasion images shown in Figure 4E. Unexpected similarities between the immunohistochemistry staining images in Figure 5D and the following previously published article from an unrelated author group:Wu J, Wang X, Yuan X, et al. Kinesin family member C1 increases temozolomide resistance of glioblastoma through promoting DNA damage repair. Cell Transplantation. 2021;30. doi: 10.1177/0963689721991466 When approached for an explanation, the authors did not respond to the queries raised by the Journal and Publisher. As verifying the validity of published work is core to the integrity of the scholarly record, we are therefore retracting the article. The corresponding author listed in this publication has been informed. We have been informed in our decision-making by our editorial policies and the COPE guidelines. The retracted article will remain online to maintain the scholarly record, but it will be digitally watermarked on each page as Retracted.

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Cite This Study

Deng et al. (2026) studied this question.

synapsesocial.com/papers/6a377f3a24f042ddf4c59e4ehttps://doi.org/10.2147/ott.s633630
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