Higher BCIS-CHIP scores strongly predicted 1-year MACCE in patients undergoing imaging-guided PCI, with an incidence of 11.7% in scores ≥5 versus 1.8% in score 0 (HR 7.4; 95% CI 2.59-21.37).
Observational (n=1,218)
Yes
Does the BCIS-CHIP score predict 1-year MACCE in patients undergoing imaging-guided PCI?
The BCIS-CHIP score effectively stratifies 1-year cardiovascular risk in patients undergoing imaging-guided PCI, with higher scores strongly predicting MACCE.
Effect estimate: HR 7.4 (95% CI 2.59-21.37)
Absolute Event Rate: 11.7% vs 1.8%
p-value: p=<0.001
BACKGROUND: A complex high-risk indicated percutaneous coronary intervention (CHIP) score was recently developed from the British Cardiovascular Intervention Society (BCIS) database, and its prognostic value has been reported. However, its utility remains non-validated in imaging-guided percutaneous coronary intervention (PCI), which has a favorable prognostic association with CHIP. We investigated the usefulness of the BCIS-CHIP score under imaging-guided PCI. METHODS: This multicenter prospective observational study included patients who underwent imaging-guided PCI. Patients were evaluated and categorized into four groups based on BCIS-CHIP scores (0, 1-2, 3-4, ≥5), for which we assessed the incidence of 1-year major adverse cardiac or cerebrovascular events (MACCE), including all-cause death, nonfatal myocardial infarction, and nonfatal stroke. Secondary outcomes were individual MACCE components, target vessel revascularization, and heart failure events. RESULTS: In total, 1218 patients were included. MACCE at 1 year occurred in 1.8%, 3.4%, 7.3%, and 11.7% of patients with BCIS-CHIP scores 0, 1-2, 3-4, and ≥5, respectively (p<0.001). The incidence of a primary endpoint in groups 3-4 (HR: 4.2, 95% CI: 1.48-12.2) and ≥5 (HR: 7.4, 95% CI: 2.59-21.37) was significantly higher than those in group 0. CONCLUSIONS: The BCIS-CHIP score is useful for predicting cardiovascular events in patients who have undergone imaging-guided PCI and could simplify risk stratification of patients with CHIP.
Nakata et al. (2026) conducted an observational in Imaging-guided percutaneous coronary intervention (n=1,218). BCIS-CHIP score ≥5 vs. BCIS-CHIP score 0 was evaluated on 1-year major adverse cardiac or cerebrovascular events (MACCE) (HR 7.4, 95% CI 2.59-21.37, p=<0.001). Higher BCIS-CHIP scores strongly predicted 1-year MACCE in patients undergoing imaging-guided PCI, with an incidence of 11.7% in scores ≥5 versus 1.8% in score 0 (HR 7.4; 95% CI 2.59-21.37).