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May 29, 2022Angiology68 citations

Evaluation of Intermountain Risk Score for Short- and Long-Term Mortality in ST Elevation Myocardial Infarction Patients

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TÇTufan ÇınarFŞFaysal ŞaylıkTATayyar Akbulut

Key Result

The Intermountain Risk Score independently predicted short-term mortality (HR 1.482; 95% CI 1.325-1.675; p<0.001) and was non-inferior to TIMI and GRACE scores in STEMI patients.

Study Design

Type

Cross-Sectional (n=1,057)

Structured PICO

Does the Intermountain Risk Score (IMRS) predict short- and long-term mortality in patients with STEMI compared to TIMI and GRACE scores?

P
Population
1,057 consecutive patients with ST elevation myocardial infarction evaluated for short- and long-term mortality.
E
Exposure
Intermountain Risk Score (IMRS) assessment
C
Comparator
Thrombolysis in Myocardial Infarction (TIMI) and Global Registry of Acute Coronary Events (GRACE) risk scores
O
Outcome
Short- and long-term mortalityhard clinical

The Intermountain Risk Score is an independent predictor of short- and long-term mortality in STEMI patients, performing non-inferiorly to established TIMI and GRACE scores.

Main Result

Hazard Ratio: 1.482 (95% CI 1.325–1.675)

p-value: p=<0.001

Abstract

The aim of this study was to examine the Intermountain Risk Score (IMRS) for short- and long-term mortality in ST elevation myocardial infarction (STEMI) patients and compare it with the well-known risk scores, such as the Thrombolysis in Myocardial Infarction (TIMI) and the Global Registry of Acute Coronary Events (GRACE). In this retrospective and cross-sectional study, 1057 consecutive patients with STEMI were evaluated. The end-points of the study were short- and long-term mortality. The overall mortality rate was 16% (n = 170 patients). The IMRS was significantly higher in STEMI patients who did not survive compared with those who survived. According to multivariable COX proportional regression analysis, the IMRS was independently related to both short- (HR: 1.482, 95% CI: 1.325-1.675, p < .001) and long-term mortality (HR: 1.915, 95% CI: 1.711-2.180, p < .001). The comparison of receiver operating characteristic curves revealed that the IMRS had non-inferior predictive capability for short- and long-term mortality than the TIMI and GRACE risk scores. To the best of our knowledge, this is the first study to show that the IMRS can predict short- and long-term prognosis of patients with STEMI. Further, the IMRS' predictive value for overall mortality was non-inferior compared with TIMI and GRACE scores.

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Cite This Study

Çınar et al. (2022) conducted a cross-sectional in ST elevation myocardial infarction (STEMI) (n=1,057). Intermountain Risk Score (IMRS) vs. TIMI and GRACE risk scores was evaluated on Short-term mortality (HR 1.482, 95% CI 1.325-1.675, p=<0.001). The Intermountain Risk Score independently predicted short-term mortality (HR 1.482; 95% CI 1.325-1.675; p<0.001) and was non-inferior to TIMI and GRACE scores in STEMI patients.

synapsesocial.com/papers/6a51a0adccac8b7790d5bc24https://doi.org/10.1177/00033197221105753
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