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July 11, 2024Journal of Biomedical Science236 citationsOpen Access

Exosomes: a review of biologic function, diagnostic and targeted therapy applications, and clinical trials

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YCYi‐Fan ChenFLFrank LuhYHYuan‐Soon Ho

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Abstract

Exosomes are extracellular vesicles generated by all cells and they carry nucleic acids, proteins, lipids, and metabolites. They mediate the exchange of substances between cells,thereby affecting biological properties and activities of recipient cells. In this review, we briefly discuss the composition of exocomes and exosome isolation. We also review the clinical applications of exosomes in cancer biology as well as strategies in exosome-mediated targeted drug delivery systems. Finally, the application of exosomes in the context of cancer therapeutics both in practice and literature are discussed.

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Cite This Study

Chen et al. (2024) studied this question.

synapsesocial.com/papers/6a548936775976cf0f087075https://doi.org/10.1186/s12929-024-01055-0
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