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Cerium oxide nanoparticles (CeO 2 particles) are exceptional lanthanide nanomaterials noted for their redox activity, oxygen storage capacity, and free radical scavenging abilities, making them highly regarded in biomedical applications due to their surface self-regeneration and other beneficial properties. In this review, we present nanoengineering methods, which have produced increased nanoceria performance in biomedical applications. More precisely, this review presents: (1) the methods of synthesis for either non- and porous cerium oxide particles will be briefly discussed; (2) the focus will be on the parameters of CeO 2 particles that have an impact on their biological properties and their use, (3) example for application in drug delivery and (4) future outlook of the cerium oxide nanoparticle.
Chesneau et al. (2025) studied this question.