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July 20, 2026Journal of Applied Physiology0 citationsOpen Access

Resistance Training Improves Cardiovascular Health in Postmenopausal Women: Systematic Review and Meta-Analysis

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SRSonia Liliana Rivera-MejíaMRMaría Rúa-AlonsoJRJéssica Rial-Vázquez

Key Result

Resistance training in postmenopausal women significantly reduced systolic blood pressure (Hedges' g 0.68; 95% CI 0.40-0.96), diastolic blood pressure, mean blood pressure, and resting heart rate.

Key Points

  • The review seeks to understand the effects of resistance training on cardiovascular and autonomic function in postmenopausal women.
  • Systematic review and meta-analysis of randomized and non-randomized trials with interventions of resistance training lasting at least 4 weeks.
  • Literature search across multiple databases including PubMed and Scopus, assessing studies up to February 2026.
  • Primary outcomes included resting heart rate, systolic and diastolic blood pressure, and mean blood pressure.
  • Significant reductions in resting heart rate, systolic blood pressure, diastolic blood pressure, and mean blood pressure after resistance training.
  • Effect sizes were small for heart rate (g=0.30) and diastolic blood pressure (g=0.37), with moderate effects observed for systolic blood pressure (g=0.68) and mean blood pressure (g=0.68).
  • Qualitative synthesis showed modest improvements in vascular adaptations and heart rate variability, with no adverse cardiac structural changes reported.

Study Design

Type

Meta-Analysis

Structured PICO

Does resistance training improve resting heart rate and blood pressure in postmenopausal women?

P
Population
60 randomized and non-randomized controlled trials evaluating resistance training interventions of ≥4 weeks in postmenopausal women.
I
Intervention
Resistance training interventions (≥4 weeks)
C
Comparator
Control (from randomized and non-randomized controlled trials)
O
Outcome
Resting heart rate (HR), systolic blood pressure (SBP), diastolic blood pressure (DBP) and mean blood pressure (MBP)surrogate

Resistance training for at least 4 weeks produces favorable hemodynamic adaptations, including significant reductions in systolic and mean blood pressure, in postmenopausal women without adverse cardiac structural changes.

Main Result

Standardized Mean Difference: 0.68 (95% CI 0.4–0.96)

Abstract

Postmenopausal women (PW) experience hemodynamic and autonomic alterations that increase cardiovascular risk. While aerobic exercise is widely recognized for its cardioprotective benefits, the chronic effects of resistance training (RT) on cardiovascular and autonomic function in this population remain less established. This systematic review aimed to evaluate the effects of RT on hemodynamic and vascular structure and function, cardiovascular autonomic control and cardiac structural outcomes in PW. A comprehensive search of PubMed, Scopus, Web of Science, and SPORTDiscus was conducted up to February 2026. Randomized and non-randomized controlled trials investigating RT interventions (≥4 weeks) were included. Primary outcomes were resting heart rate (HR), systolic blood pressure (SBP), diastolic blood pressure (DBP) and mean blood pressure (MBP). Secondary outcomes included vascular adaptations, heart rate variability (HRV), and cardiac structural characteristics. Meta-analyses were performed using a random-effects model, with pooled effects expressed as Hedges’ g; heterogeneity was quantified using I 2 . Risk of bias, reporting quality exercise parameters, and methodological consistency were assessed. 60 studies met inclusion criteria. Meta-analyses showed statistically significant reductions in HR, SBP, DBP, and MBP after RT. The magnitude of the effects, was small for HR (g=0.30, 95% CI 0.02;0.58, I 2 =0.0%) and DBP (g=0.37, 95% CI 0.11;0.63, I 2 =0.0%) and moderate effects for SBP (g=0.68, 95% CI 0.40;0.96, I 2 =0.0%) and MBP (g=0.68, 95% CI 0.37;0.99, I 2 =0.0%). Qualitative synthesis showed modest improvements in vascular adaptations and HRV, while echocardiographic studies reported no adverse structural cardiac adaptations. RT produces favorable cardiovascular and autonomic adaptations in PW, improving hemodynamic regulation without structural cardiac alterations.

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Cite This Study

Rivera-Mejía et al. (2026) conducted a meta-analysis in Postmenopausal women. Resistance training vs. Control was evaluated on Systolic blood pressure (SBP) (Hedges' g 0.68, 95% CI 0.40-0.96). Resistance training in postmenopausal women significantly reduced systolic blood pressure (Hedges' g 0.68; 95% CI 0.40-0.96), diastolic blood pressure, mean blood pressure, and resting heart rate.

synapsesocial.com/papers/6a5dba3f8bd453d3397ab6b9https://doi.org/10.1152/japplphysiol.01180.2025
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