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January 1, 2008Organic & Biomolecular Chemistry127 citationsOpen Access

A modular flow reactor for performing Curtius rearrangements as a continuous flow process

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MBMarcus BaumannIBIan R. BaxendaleSLSteven V. Ley

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Abstract

The use of a mesofluidic flow reactor is described for performing Curtius rearrangement reactions of carboxylic acids in the presence of diphenylphosphoryl azide and trapping of the intermediate isocyanates with various nucleophiles.

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Baumann et al. (2008) studied this question.

synapsesocial.com/papers/6a62016d5a5e300a3289c723https://doi.org/10.1039/b801631n
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