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September 9, 2014Angewandte Chemie International Edition120 citationsOpen Access

The Isomerization of Allylrhodium Intermediates in the Rhodium‐Catalyzed Nucleophilic Allylation of Cyclic Imines

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HHHamish B. HepburnHLHon Wai Lam

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Abstract

Allylrhodium species generated from potassium allyltrifluoroborates can undergo isomerization by 1,4-rhodium(I) migration to give more complex isomers, which then react with cyclic imines to provide products with up to three new stereochemical elements. High enantioselectivities are obtained using chiral diene-rhodium complexes.

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Cite This Study

Hepburn et al. (2014) studied this question.

synapsesocial.com/papers/6a62638f5d85cff801c97097https://doi.org/10.1002/anie.201407233
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