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June 2, 2022Eurosurveillance86 citationsOpen Access

SARS-CoV-2 Omicron variants BA.1 and BA.2 both show similarly reduced disease severity of COVID-19 compared to Delta, Germany, 2021 to 2022

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CSClaudia SieversBZBenedikt ZacherAUAlexander Ullrich

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Abstract

German national surveillance data analysis shows that hospitalisation odds associated with Omicron lineage BA.1 or BA.2 infections are up to 80% lower than with Delta infection, primarily in ≥ 35-year-olds. Hospitalised vaccinated Omicron cases' proportions (2.3% for both lineages) seemed lower than those of the unvaccinated (4.4% for both lineages). Independent of vaccination status, the hospitalisation frequency among cases with Delta seemed nearly threefold higher (8.3%) than with Omicron (3.0% for both lineages), suggesting that Omicron inherently causes less severe disease.

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Sievers et al. (2022) studied this question.

synapsesocial.com/papers/6a63293baca57fe965288ba5https://doi.org/10.2807/1560-7917.es.2022.27.22.2200396
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